Efficient unified synthesis of diverse bridged polycyclic scaffolds using a complexity-generating ‘stitching’ annulation approach?
Chemical Communications Pub Date: 2020-12-21 DOI: 10.1039/D0CC06975B
Abstract
Regioselective and stereospecific directed C–H arylation of simple amine substrates, and cyclisation, delivered 30 diverse, three-dimensional scaffolds. The unified approach significantly expanded the range of bridged ring systems that contain both a nitrogen atom and an aromatic ring.
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4