First total synthesis of cryptomoscatone F1?

RSC Advances Pub Date: 2015-04-01 DOI: 10.1039/C5RA03693C

Abstract

The total synthesis of cryptomoscatone F1 has been accomplished for the first time. The strategy involves chelation-controlled allylation, the addition of alkylzinc to an aldehyde and olefin cross-metathesis reactions as key steps. a new route to a vinyl lactone was explored.

Graphical abstract: First total synthesis of cryptomoscatone F1
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