Fluorescence and biological stabilization of phosphorus-functionalized mesoporous silica nanospheres modified with a bis(8-hydroxyquinoline) zinc complex?

Materials Advances Pub Date: 2021-09-07 DOI: 10.1039/D1MA00636C

Abstract

Green-emitting phosphorus-functionalized mesoporous silica (PMPS) nanospheres were fabricated by modifying their surfaces with (8-hydroxyquinoline) zinc (Znq2). A simulated body fluid soaking test and subsequent gas-adsorption measurements revealed that Znq2-modification could dramatically suppress the biodegradation of the nanospheres. This study establishes Znq2 as a novel and potential surface modifier of mesoporous silicas and demonstrates that effective surface design of the hosts will allow the exploitation of potential functionalities of the modifier.

Graphical abstract: Fluorescence and biological stabilization of phosphorus-functionalized mesoporous silica nanospheres modified with a bis(8-hydroxyquinoline) zinc complex
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