Facile synthesis of azaarene-2-substituted chromanone derivatives via tandem sp3 C–H functionalization/decarboxylation of azaarenes with 4-oxo-4H-chromene-3-carboxylic acid?
RSC Advances Pub Date: 2014-10-03 DOI: 10.1039/C4RA09338K
Abstract
A facile catalyst-free tandem sp3 C–H functionalization/decarboxylation of 4-oxo-4H-chromene-3-carboxylic acid with 2-alkylazaarenes was developed, which can efficiently construct azaarene 2-substituted chromanones in moderate to good yields. This method proves to be efficient and innovative and the biologically significant azaarene 2-substituted chromanones can be accessed in a single step through this methodology.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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