Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids?

Chemical Communications Pub Date: 2015-02-09 DOI: 10.1039/C4CC09780G

Abstract

A new methodology for the synthesis of side chain mono- or bis-methylated Fmoc-Dap, -Dab and -Orn amino acids was developed by probing the reactivity of commercially available Fmoc amino acids.

Graphical abstract: Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids
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