Facile and general syntheses of 3- and/or 5-substituted 7H-pyrazolo[4,3-e]-1,2,4-triazolo[4,3-c]pyrimidines as a new class of potential xanthine oxidase inhibitors?
Chemical Communications Pub Date: 1900-01-01 DOI: 10.1039/A903676H
Abstract
Convenient syntheses of 3- and/or 5-substituted 7H-pyrazolo[4,3-e]-1,2,4-triazolo[4,3-c]pyrimidines as a new class of potent xanthine oxidase inhibitors, involving the oxidative cyclisation of 4-alkylidenehydrazino- or 4-arylmethylidenehydrazino-1H-pyrazolo[3,4-d]pyrimidines with 70% nitric acid as the key step, are described.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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