Direct, rapid, solvent-free conversion of unactivated esters to amides using lithium hydroxide as a catalyst?

RSC Advances Pub Date: 2015-10-20 DOI: 10.1039/C5RA21394K

Abstract

A simple, solvent-free methodology is reported for the direct conversion of esters to amides using lithium hydroxide as a catalyst. The approach allows for the preparation of a range of amide products as well as being applicable to the ring-opening of a representative lactone.

Graphical abstract: Direct, rapid, solvent-free conversion of unactivated esters to amides using lithium hydroxide as a catalyst
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