Efficient singlet oxygen generation from sugar pendant C60 derivatives for photodynamic therapy?
Chemical Communications Pub Date: 2015-09-17 DOI: 10.1039/C5CC07353G
Abstract
The amidation reaction between C60 with an activated ester group (1) and acetylated Glc (AcGlc) with an amino group (2) was performed to yield the target AcGlc-pendant C60 compound (3). The water soluble deacetylated compound, Glc-pendant C60 compound (4), exhibited high photocytotoxicity against HeLa cells due to the more efficient singlet oxygen generation as compared with that of Glc-pendant azafulleroids.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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