Enantioselective total synthesis of periconiasin A?

Organic Chemistry Frontiers Pub Date: 2017-12-01 DOI: 10.1039/C7QO00952F

Abstract

A concise, enantioselective total synthesis of periconiasin A, a hybrid natural product, has been achieved, featuring a ring closing metathesis (RCM) reaction and a Suzuki coupling to secure a (Z,E,E)-skipped triene system and an intramolecular Diels–Alder (IMDA) reaction to construct the challenging 6–9 fused ring system.

Graphical abstract: Enantioselective total synthesis of periconiasin A
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