Enantioselective synthesis of C3 fluoro-MEP

Organic & Biomolecular Chemistry Pub Date: 2006-11-10 DOI: 10.1039/B613656G

Abstract

The first enantioselective synthesis of C3 fluoro-MEP is herein reported. The synthetic pathway developed takes advantage of a selective hydrofluorination of a 2,3-epoxy-1-alcohol to introduce the required tertiary fluoride unit.

Graphical abstract: Enantioselective synthesis of C3 fluoro-MEP
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