Enamine-assisted facile generation of trifluoroacetaldehyde from trifluoroacetaldehyde ethyl hemiacetal and its carbon–carbon bond forming reaction leading to β-hydroxy-β-trifluoromethyl ketones
Chemical Communications Pub Date: 1900-01-01 DOI: 10.1039/A804922J
Abstract
Trifluoroacetaldehyde ethyl hemiacetal 1 readily reacts with various enamines 2 in hexane at room temperature for 1 h to give the corresponding β-hydroxy-β-trifluoromethyl ketones in good yields.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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