Efficient access to 1H-indazoles via copper-catalyzed cross-coupling/cyclization of 2-bromoaryl oxime acetates and amines?
Organic Chemistry Frontiers Pub Date: 2014-11-12 DOI: 10.1039/C4QO00244J
Abstract
We describe a novel and useful method to provide 1H-indazoles via copper-catalyzed tandem reaction which is triggered by an Ullmann-type reaction and followed by N–N bond formation. Arylamines, alkylamines and sulfonamides could smoothly couple with 2-bromoaryl oxime acetates and various 1H-indazoles were formed in good to excellent yields under mild reaction conditions.
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Journal Name：Organic Chemistry Frontiers
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CAS no.: 89640-58-4
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