Efficient C2 functionalisation of 2H-2-imidazolines
Organic & Biomolecular Chemistry Pub Date: 2007-11-08 DOI: 10.1039/B713065A
Abstract
Alkylation and oxidation of 2H-2-imidazolines, followed by regioselective deprotection, thionation and microwave-assisted Liebeskind–Srogl reaction, efficiently led to 2-aryl-2-imidazolines as new analogues of p53-hdm2 interaction inhibitors (Nutlins).
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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