Engineering of d-fructose-6-phosphate aldolase A for improved activity towards cinnamaldehyde?

Catalysis Science & Technology Pub Date: 2016-12-14 DOI: 10.1039/C6CY01622G

Abstract

D-Fructose-6-phosphate aldolase A (FSAA) from Escherichia coli was engineered for enhanced catalytic efficiency towards cinnamaldehyde. The result implies that the site 59 residue possibly affects the activity of FSAA towards cinnamaldehyde through a residue interaction network rather than binding to the catalytic water as generally regarded.

Graphical abstract: Engineering of d-fructose-6-phosphate aldolase A for improved activity towards cinnamaldehyde
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