Dynamic visualization of type II peptidyl carrier protein recognition in pyoluteorin biosynthesis?
RSC Chemical Biology Pub Date: 2020-03-24 DOI: 10.1039/C9CB00015A
Abstract
Using a covalent chemical probe and X-ray crystallography coupled to nuclear magnetic resonance data, we elucidated the dynamic molecular basis of protein recognition between the carrier protein and adenylation domain in pyoluteorin biosynthesis. These findings reveal a unique binding mode, which contrasts previously solved carrier protein and partner protein interfaces.
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Journal Name：RSC Chemical Biology
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CAS no.: 89640-58-4
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