Cu-catalyzed intermolecular oxyalkylation of styrenes under air: access to diverse iminolactones?

RSC Advances Pub Date: 2017-08-25 DOI: 10.1039/C7RA07306B

Abstract

A practical, simple, and efficient copper-catalyzed highly regioselective oxyalkylation of styrenes and readily available α-bromoacetamides under air is realized. This reaction exhibits a wide range of functional group tolerance in styrenes and α-bromoacetamides to afford iminolactones.

Graphical abstract: Cu-catalyzed intermolecular oxyalkylation of styrenes under air: access to diverse iminolactones
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