A highly diastereoselective, catalytic three-component assembly reaction for the synthesis of spiropyrrolidinyloxindoles?

Chemical Communications Pub Date: 2006-11-06 DOI: 10.1039/B609155E

Abstract

Spiropyrrolidinyloxindole compounds are synthesized in moderate to excellent yield via a highly diastereoselective Cu(I)-catalysed three-component assembly reaction of an imine, diazo-compound and substituted olefin dipolarophile.

Graphical abstract: A highly diastereoselective, catalytic three-component assembly reaction for the synthesis of spiropyrrolidinyloxindoles
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