Copper-catalyzed ortho-C–H amination of protected anilines with secondary amines?

Chemical Communications Pub Date: 2014-02-03 DOI: 10.1039/C3CC49633C

Abstract

A practical Cu-catalyzed picolinamide-directed o-amination of anilines showing excellent mono-substitution selectivity and high functional group tolerance has been developed.

Graphical abstract: Copper-catalyzed ortho-C–H amination of protected anilines with secondary amines
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