Copper-catalysed oxidative Csp3–H methylenation to terminal olefins using DMF?

Chemical Communications Pub Date: 2014-05-21 DOI: 10.1039/C4CC02275K

Abstract

A copper-catalysed direct oxidative Csp3–H methylenation to terminal olefins using DMF as one carbon source was developed. In this reaction, various functional groups were well tolerated, thus providing a simple way to construct arylvinylketones and arylvinylpyridines. The preliminary mechanistic investigations revealed that CH2 was from DMF (N–CH3).

Graphical abstract: Copper-catalysed oxidative Csp3–H methylenation to terminal olefins using DMF
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