A gold-catalysed imine–propargylamine cascade sequence: synthesis of 3-substituted-2,5-dimethylpyrazines and the reaction mechanism?
Chemical Communications Pub Date: 2014-03-13 DOI: 10.1039/C4CC01485E
Abstract
The gold-catalysed coupling reaction between propargylamine-derived imines and propargylamine exclusively afforded pyrazines. Besides, in order to understand the mechanism of this sequence, deuterium labeling and computational studies have been performed.
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4