Dyeing fungi: amphotericin B based fluorescent probes for multiplexed imaging?
Chemical Communications Pub Date: 2021-01-19 DOI: 10.1039/D0CC08177A
Abstract
The clinically used antifungal polyene amphotericin B was conjugated, via the mycosamine and the aglycon moieties, to fluorophores. The Cy5 conjugated probe showed selective labelling of fungi in the presence of bacteria, allowing multiplexed imaging and identification of microbial species in a co-culture of fungi and Gram-positive and Gram-negative bacteria.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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