Diastereoselective synthesis of substituted diaziridines from simple ketones and aldehydes?
Chemical Communications Pub Date: 2015-07-21 DOI: 10.1039/C5CC04813C
Abstract
Diastereopure substituted diaziridines from simple ketones, aldehydes and amines are here reported. These important chemical scaffolds are obtained in the presence of a weak inorganic base and hydroxylamine O-sulfonic acid (HOSA). This method introduces three stereocenters in one step to provide a wide variety of substituted diaziridines with high yields and diastereoselectivities.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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