A general iodine-mediated synthesis of primary sulfonamides from thiols and aqueous ammonia?
Organic & Biomolecular Chemistry Pub Date: 2016-06-28 DOI: 10.1039/C6OB01301E
Abstract
A general and efficient methodology for preparing primary sulfonamides has been developed. In the presence of iodine as the catalyst and TBHP (70% in water) as the oxidant, a wide range of primary sulfonamides were prepared from the corresponding thiols and aqueous ammonia in moderate to good yields.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4