Development of a novel oxidatively removable and recyclable linker for combinatorial solid phase synthesis

Chemical Communications Pub Date: 2000-02-23 DOI: 10.1039/A909236F

Abstract

An appropriately derivatized phenanthridine is shown to behave as a novel, reusable linker which is based on a disubstituted amide anchorage and forms an acid group on oxidative cleavage, but tolerates exposure to acidic, basic and reductive reaction conditions.

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