Determination of triamcinolone acetonide in cream and suspension formulations by high-performance liquid chromatography
ANALYSTANALYST Pub Date: DOI: 10.1039/AN9760100876
Abstract
Methods are described for the determination of triamcinolone acetonide at concentrations of 0.025 and 0.1%m/m in creams and 2 and 6 mg ml–1 in suspensions. Triamcinolone acetonide extracted from these formulations is assayed by high-performance liquid chromatography, using a reversed-phase separation on a Spherisorb S10 ODS column with a solvent system of methanol and water. Prednisolone is used as an internal standard.
The main advantages of the method are the over-all speed of analysis and the degree of precision obtained.
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CAS no.: 89640-58-4
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