Cp*Rh(iii)-catalyzed C(sp3)–H alkylation of 8-methylquinolines in aqueous media?
Chemical Communications Pub Date: 2017-01-30 DOI: 10.1039/C6CC09830D
Abstract
The rhodium(III)-catalyzed cross-coupling reaction of 8-methylquinolines with a range of allylic alcohols in water is described. This approach leads to the synthesis of various γ-quinolinyl carbonyl compounds, which are synthetically useful precursors for the construction of bioactive tetrahydroquinoline and azasteroid derivatives.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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