Copper-catalyzed cascade synthesis of benzimidazoquinazoline derivatives under mild condition?

Chemical Communications Pub Date: 2011-04-01 DOI: 10.1039/C1CC10383K

Abstract

A convenient and efficient copper-catalyzed cascade method has been developed for the synthesis of benzimidazoquinazoline derivatives via reactions of readily available substituted 2-(2-halophenyl)benzoimidazoles with amidines or guanidine under mild conditions (even at room temperature).

Graphical abstract: Copper-catalyzed cascade synthesis of benzimidazoquinazoline derivatives under mild condition
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