Decarboxylative cascade cyclization of α-keto acids with 2-cyano-3-arylaniline-derived acrylamides?
Organic & Biomolecular Chemistry Pub Date: 2019-10-15 DOI: 10.1039/C9OB02023C
Abstract
An oxidative decarboxylative cascade cyclization of α-keto acids with 2-cyano-3-arylaniline-derived acrylamides was developed. This cascade reaction exhibits a broad substrate scope, and provides an efficient access to carbonyl-containing pyrido[4,3,2-gh]phenanthridines. A possible mechanism is proposed.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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