Copper(i)-catalyzed intermolecular cyanoarylation of alkenes: convenient access to α-alkylated arylacetonitriles?
Organic & Biomolecular Chemistry Pub Date: 2020-06-22 DOI: 10.1039/D0OB01055C
Abstract
A novel Cu(I)-catalyzed intermolecular cyanoarylation of alkenes with diaryliodonium salts as a radical arylating reagent and tetra-butylammonium cyanide as an electrophilic cyanating reagent was established. A broad range of α-alkylated arylacetonitriles were efficiently constructed in good to excellent yields under base- and oxidant-free and mild conditions.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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