Copper-catalyzed endo-type trifluoromethylarylation of alkynes?

Chemical Communications Pub Date: 2014-09-01 DOI: 10.1039/C4CC05692B

Abstract

A new copper-catalyzed trifluoromethylarylation reaction of alkynes has been developed. The transformation represents the first example of endo-type carbotrifluoromethylation of unsaturated carbon–carbon bonds and provides efficient access to a variety of CF3-substituted dihydronaphthalenes and chromenes.

Graphical abstract: Copper-catalyzed endo-type trifluoromethylarylation of alkynes
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