Copper-catalyzed thiocarbonylation and thiolation of alkyl iodides?

Organic & Biomolecular Chemistry Pub Date: 2022-01-11 DOI: 10.1039/D2OB00008C

Abstract

In the present study, an efficient Cu-catalyzed transthiolation of alkyl iodides is developed. Notably, in the presence of CO, thioesters could also be obtained with copper and cobalt as the co-catalyst. This transformation displayed good functional group tolerance and afforded thioesters or sulfides from the corresponding alkyl iodides.

Graphical abstract: Copper-catalyzed thiocarbonylation and thiolation of alkyl iodides
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