Copper-catalyzed selective oxidation of hydrazones through C(sp3)–H functionalization?
Organic & Biomolecular Chemistry Pub Date: 2021-09-27 DOI: 10.1039/D1OB01563J
Abstract
A simple and mild protocol for copper-catalyzed oxidation of hydrazones at the α-position has been reported. Various substrates are compatible, providing the corresponding products in moderate to good yields. This strategy provides an efficient and convenient solution for the synthesis of carbonyl hydrazone. A free radical pathway mechanism is suggested for the transformation.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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