Copper-catalyzed ortho-halogenation of arenes and heteroarenes directed by a removable auxiliary?
Chemical Communications Pub Date: 2015-02-17 DOI: 10.1039/C5CC00531K
Abstract
Copper-catalyzed ortho-halogenation of C(sp2)–H bonds directed by a PIP directing group with NXS (X = Cl, Br, I) has been developed. The reaction is scalable and tolerates a broad range of functional groups and heteroarenes, providing an efficient access to halogenated arenes and heteroarenes.
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4