Construction of protected hydroxylated pyrrolidines using nitrogen-centered radical cyclizations?

Chemical Communications Pub Date: 2009-09-02 DOI: 10.1039/B914757H

Abstract

Nitrogen-centered radical cyclizations onto silyl enol ethers were utilized for the syntheses of protected polyhydroxylated pyrrolidines 2-hydroxymethyl-3-hydroxypyrrolidine and 1,4-dideoxy-1,4-imino-L-ribitol.

Graphical abstract: Construction of protected hydroxylated pyrrolidines using nitrogen-centered radical cyclizations
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