A facile one-pot synthesis of 2,3-diarylated benzo[b]furans via relay NHC and palladium catalysis?
Organic & Biomolecular Chemistry Pub Date: 2016-01-05 DOI: 10.1039/C5OB02336J
Abstract
An efficient one-pot synthesis of 2,3-diarylated benzo[b]furans was realized through the relay catalysis of N-Heterocyclic Carbene (NHC) and palladium from substituted 2′-bromodiphenylbromomethanes and aryl aldehydes. The easy availability of the starting materials, good compatibility of catalysts, convergent assembly and concomitant modification of the target scaffold, and potential utilization value of the products make this strategy attractive in organic synthesis.
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Journal Name:Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4