Condensation of anthranilic acids with pyridines to furnish pyridoquinazolones via pyridine dearomatization?
Chemical Communications Pub Date: 2016-10-05 DOI: 10.1039/C6CC07365D
Abstract
The unprecedented carbodiimide-mediated condensation between pyridines and anthranilic acids via pyridine dearomatization at room temperature has been developed to provide a straightforward approach to pyridoquinazolones. The value of this approach has further been demonstrated by its application to one-step, gram-scale syntheses of a series of pyridoquinazolone-based natural products and their analogues from readily available starting materials.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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