A double-triggered self-immolative spacer for increased selectivity of molecular release?

Organic & Biomolecular Chemistry Pub Date: 2021-12-01 DOI: 10.1039/D1OB02124A

Abstract

A self-immolative spacer based on dissymmetrical N,N′-bis-carbamate aniline is introduced to liberate a substrate from a precursor after dual activation. The proof of principle of its exclusive selectivity for substrate liberation has been conducted on a profluorophore.

Graphical abstract: A double-triggered self-immolative spacer for increased selectivity of molecular release
Recommended Literature