Biosynthesis of polyketides by trans-AT polyketide synthases

Natural Product Reports Pub Date: 2015-12-22 DOI: 10.1039/C5NP00125K

Abstract

Covering 2000 to June 2015

This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that represents one of the major group of proteins involved in the production of bioactive polyketides. The article includes 609 references and covers the literature from 2009 through June 2015.

Graphical abstract: Biosynthesis of polyketides by trans-AT polyketide synthases
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