Concise synthesis of bicyclic aminals and their evaluation as precursors to the sarain core

Organic & Biomolecular Chemistry Pub Date: 2008-06-19 DOI: 10.1039/B806031B

Abstract

A number of bicyclic aminals have been prepared in a stereospecific manner as potential precursors to the core structure of the sarain alkaloids. Rearrangement of these aminals to new diazabicyclic and diazatricyclic systems has been observed under various conditions.

Graphical abstract: Concise synthesis of bicyclic aminals and their evaluation as precursors to the sarain core
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