Thiomorpholines
Thiomorpholines are a class of organic compounds containing a secondary amine group and a sulfur atom in their molecular structure. These molecules exhibit unique chemical properties due to the presence of both nitrogen and sulfur functionalities, making them versatile intermediates in synthetic chemistry. Thiomorpholine derivatives can be synthesized through various reactions such as amidation or sulfonation processes, offering researchers multiple routes for functionalization.
Thiomorpholines are particularly useful in pharmaceuticals, where they serve as precursors to drugs with specific biological activities. Their ability to form hydrogen bonds and interact with biomolecules makes them valuable tools in drug discovery and development. Additionally, thiomorpholine compounds have applications in agrochemicals, acting as fungicides or herbicides due to their selective toxicity against certain plant pathogens.
In analytical chemistry, these compounds are also utilized as solvents or reagents for improving the detection of specific analytes. The unique properties of thiomorpholines make them indispensable in various research and industrial settings, contributing significantly to the advancement of chemical technology.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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(thiomorpholin-3-yl)methanol | 58729-32-1 | C5H11NOS |
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4-Thiomorpholinecarboxaldehyde,2-methyl- | 30188-21-7 | C6H11NOS |
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2,3-dimethylthiomorpholine-4-carbaldehyde, Mixture of diastereomers | 31507-18-3 | C7H13NOS |
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4-Thiomorpholinecarboxaldehyde | 61907-20-8 | C5H9NOS |
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3-Thiomorpholinone, 4-methyl- | 75469-02-2 | C5H9NOS |
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| 137860-92-5 | C6H10ClNOS |
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cyclopent[2,3]azirino[2,1-b]thiazol-7(4ah)-one,2,3-dihydro-4a-methyl- | 71310-16-2 | C8H9NOS |
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1H,3H-Thiazolo[4,3-c][1,4]thiazine-3-thione,tetrahydro- | 7447-45-2 | C6H9NS3 |
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4-(oxolane-3-carbonyl)thiomorpholine | 1436160-61-0 | C9H15NO2S |
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1689944-37-3 | C7H15NOS |
Related Literature
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Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
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Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
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Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
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Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
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