Sulfanylbenzoic acids and derivatives
Sulfanylbenzoic acids and their derivatives are a class of organic compounds characterized by the presence of a sulfide (-S-) group attached to a benzoic acid moiety. These compounds exhibit diverse chemical properties due to the conjugation between the aromatic ring and the sulfur-containing functional group, leading to unique reactivity patterns in synthesis and biological applications.
Structurally, these acids can exist as unsubstituted or substituted derivatives, offering flexibility in their design for various purposes such as pharmaceuticals, agrochemicals, and material sciences. The introduction of different substituents at the aromatic ring positions can influence solubility, stability, and bioavailability, making them valuable intermediates in organic synthesis.
In terms of applications, sulfanylbenzoic acids and derivatives have been explored for their potential as anticancer agents due to their ability to modulate specific cellular pathways. Additionally, they serve as precursors for the development of sensors and probes in analytical chemistry, exploiting their characteristic spectral properties. The versatility of these compounds makes them a focal point in both academic research and industrial applications.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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Ethyl 4-bromo-2-(methylthio)benzoate | 918328-04-8 | C10H11BrO2S |
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2-(Methylthio)benzoic acid | 3724-10-5 | C8H8O2S |
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2-Chloro-5-(methylthio)benzoic acid | 51546-12-4 | C8H7ClO2S |
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Benzoic acid, 5-(chlorothio)-2-hydroxy- | 62176-14-1 | C7H5ClO3S |
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2-(Thiophen-3-ylmethyl)sulfanylbenzoic Acid | 62688-29-3 | C12H10O2S2 |
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Benzamide, N-ethyl-2-mercapto- | 65382-84-5 | C9H11NOS |
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5-chloro-2-sulfanylbenzoic acid | 20324-50-9 | C7H5ClO2S |
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Benzoic acid,2-chloro-6-mercapto- | 20324-51-0 | C7H5ClO2S |
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3,3'-DTBA | 1227-49-2 | C14H10O4S2 |
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Benzoyl chloride,3-[(difluoromethyl)thio]- | 261944-16-5 | C8H5ClF2OS |
Related Literature
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Kaiyuan Huang,Wangkang Qiu,Meilian Ou,Xiaorui Liu,Zenan Liao,Sheng Chu RSC Adv., 2020,10, 18824-18829
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Raheleh Torabi,Hedayatollah Ghourchian,Massoud Amanlou Org. Biomol. Chem., 2016,14, 8141-8153
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Doug Ogrin,Laura H. van Poppel,Simon G. Bott,Andrew R. Barron Dalton Trans., 2004, 3689-3694
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Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
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