Rhazinilam alkaloids
Rhazinilam alkaloids are a group of nitrogen-containing organic compounds derived from natural sources, primarily found in the plant species Rhus coriaria. These alkaloids exhibit a range of pharmacological activities including anti-inflammatory, antipyretic, and analgesic properties. Structurally, they belong to the quaternary ammonium group, featuring a complex molecular configuration with multiple functional groups such as hydroxyl and amide moieties.
Research on rhazinilam alkaloids has shown potential therapeutic applications in managing inflammatory conditions and pain symptoms due to their ability to modulate various cellular signaling pathways. Their chemical stability and efficacy make them promising candidates for further development into pharmaceutical products, though clinical trials are necessary to validate these findings and determine optimal dosages and administration routes.
In summary, rhazinilam alkaloids represent a valuable resource in the field of medicinal chemistry, offering multifaceted therapeutic benefits that warrant deeper investigation.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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(-)-leuconolam | 109363-24-8 | C19H22N2O3 |
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6,7-Dehydroleuconoxine | 1207530-25-3 | C19H20N2O2 |
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21-O-methylleuconolam | 109305-79-5 | C20H24N2O3 |
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Leuconolam; N-Me | 160985-67-1 | C20H24N2O3 |
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Leuconoxine; 5-Deoxo, 7-hydroxy | 1432584-34-3 | C19H24N2O2 |
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Leuconoxine; 6β-Hydroxy | 1432584-31-0 | C19H22N2O3 |
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Indolizino[8,1-ef][1]benzazonine-6,13(5H,9H)-dione,8a-ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxy-, (8aR,12aS,14bS)- | 93710-27-1 | C19H22N2O3 |
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5,21-dihydrorhazinilam | 109305-80-8 | C19H24N2O |
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Leuconoxine | 155416-24-3 | C19H22N2O2 |
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Rhazinilam; (R)-form, 5,21-Dihydro, N-oxide | 1431864-00-4 | C19H24N2O2 |
Related Literature
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Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
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J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
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Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
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