Purine ribonucleoside monophosphates
Purine Ribonucleoside Monophosphates are essential intermediates in the biosynthesis of nucleic acids and play a critical role in cellular metabolism. These compounds, comprising adenylate (AMP) and guanylate (GMP), serve as key substrates for various enzymatic reactions involved in energy transfer and genetic information storage. Widely used in pharmaceutical research, these monophosphates can be converted into more complex nucleotides or utilized directly in therapeutic applications targeting metabolic disorders and cancer treatments. Additionally, they are crucial components in the development of nucleic acid-based diagnostics and gene therapy vectors due to their pivotal role in nucleotide biosynthesis pathways.
In biochemical studies, Purine Ribonucleoside Monophosphates offer researchers valuable tools for investigating purine metabolism, enzyme kinetics, and regulatory mechanisms within cellular environments. Their purity and stability make them suitable for a wide range of applications, from basic research to clinical trials, where precise control over nucleotide availability is essential.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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Gallium,dimethyl(2-methyl-2-propanolato) (9CI) | 6917-64-2 | C12H16N5O8P |
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Guanosine5'-(trihydrogen diphosphate), P'-anhydride with phosphorofluoridic acid (9CI) | 57817-57-9 | C10H15FN5O13P3 |
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5'-Xanthylic acid | 523-98-8 | C10H13N4O9P |
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ARL 67156 | 160928-38-1 | C15H24Br2N5O12P3 |
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Calcium 5'-guanylate | 38966-30-2 | C10H12CaN5O8P |
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Xanthosine 5'-monophosphate sodium salt | 25899-70-1 | C10H11N4Na2O9P |
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Adenosine 5′-phosphosulfate sodium salt | 102029-95-8 | C10H14N5NaO10PS |
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Adenosine Phosphate Disodium | 13474-03-8 | C10H13N5NaO7P |
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9H-Purin-6-amine,9-[1-[[1-[(triphenylmethoxy)methyl]ethenyl]oxy]ethenyl]- | 104532-13-0 | C11H14N5O8P |
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Adenosine, 5'-[hydrogen[[hydroxy(phosphonooxy)phosphinyl]methyl]phosphonate], dilithium salt (9CI) | 104809-20-3 | C11H17LiN5O12P3 |
Related Literature
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Xiaofeng Lin RSC Adv., 2016,6, 9002-9006
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S. Amaresh,K. Karthikeyan,K. J. Kim,Y. S. Lee RSC Adv., 2014,4, 23107-23115
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Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
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Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
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