Phenyltropanes
Phenyltropanes are a class of organic compounds characterized by the presence of an aromatic phenyl group and a tropane ring system. These molecules exhibit diverse structural variations, which contribute to their wide-ranging biological activities. Common derivatives include tropinone, hyoscyamine, and scopolamine, among others. Phenyltropanes are known for their significant pharmacological properties, including anticholinergic effects, analgesic potential, and the ability to modulate neurotransmitter systems. Their applications span from traditional medicine in certain cultures to modern pharmaceuticals used in treatments such as anti-dementia medications and muscle relaxants. Due to their complex structures, these compounds often require precise synthesis techniques and stringent quality control measures to ensure consistency and efficacy in both research and clinical settings.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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(1R,2S,3S,5S)-Methyl 3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate | 50370-56-4 | C16H20FNO2 |
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CITFP | 155797-99-2 | C18H23FINO2 |
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Methyl (1R,2S,3S,5S)-3-(4-bromophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate | 135367-08-7 | C16H20BrNO2 |
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Tesofensine citrate | 861205-83-6 | C23H31Cl2NO8 |
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RTI-111 | 150653-91-1 | C16H20Cl3NO2 |
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(1R,2R,3S,5S)-3-(3,4-Dichlorophenyl)-8-methyl-8-azabicyclo3.2.1octane-2-methanol | 173667-94-2 | C15H19Cl2NO |
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RTI 70 | 140633-58-5 | C15H18ClNO2 |
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4-methoxy-3-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)benzoic acid | 67078-20-0 | C16H21NO3 |
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N-Boc-3-(8-aza-bicyclo[3.2.1]octan-3-yl)benzamide | 949902-65-2 | C19H26N2O3 |
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1R-(exo,exo)-8-Methyl-3-phenyl-8-azabicyclo3.2.1octane-2-carboxylic Acid Methyl Ester | 50372-80-0 | C16H21NO2 |
Related Literature
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Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
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Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
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Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
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Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
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Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
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