Phenylalanine and derivatives
Phenylalanine is an essential amino acid that serves as a precursor for various biologically important molecules, including proteins, melanin, and neurotransmitters such as dopamine. It plays a critical role in the human body's metabolism and functions. Derivatives of phenylalanine include catecholamines like tyrosine, which is further metabolized to form adrenaline and noradrenaline; and other compounds such as L-DOPA (levodopa), used clinically for the treatment of Parkinson’s disease.
Phenylalanine derivatives are widely utilized in pharmaceuticals, food additives, and nutrition supplements. For instance, they can be employed as flavor enhancers or colorants due to their structural similarity to natural substances. In medical applications, L-DOPA is a key drug used to alleviate the symptoms of Parkinson's disease by providing a precursor for dopamine synthesis in the brain.
These derivatives are essential in diverse industries, highlighting their versatility and significance in both medical research and commercial products.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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TMC 52; TMC 52B, 4'-Deoxy | 213417-25-5 | C20H30N4O5 |
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Bacithrocin B1 | 160433-49-8 | C19H29N5O3 |
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L-PHENYLALANINE | 3617-44-5 | C9H11NO2 |
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Itampolin A | 911030-64-3 | C31H33Br4N3O6 |
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Itampolin A; 27ξ-Hydroxy | 911030-65-4 | C31H33Br4N3O7 |
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DL-3-Phenylalanine | 150-30-1 | C9H11NO2 |
Related Literature
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Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
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Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
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