Organic N-nitroso compounds
Organic N-nitroso compounds are a class of chemical substances characterized by the presence of an NO group attached to a nitrogen atom within a carbon-based molecule. These compounds are formed through the reaction between nitrite ions and primary or secondary amines, leading to a variety of structures depending on the parent amine used. Common applications include use as intermediates in organic synthesis, pharmaceuticals for therapeutic purposes such as anti-inflammatory agents, and as potential carcinogens due to their ability to form nitrosamines upon metabolism. Due to their reactivity, N-nitroso compounds are often studied for environmental and health implications, particularly concerning their role as suspected mutagens and carcinogens. Research into the synthesis, properties, and mechanisms of action of these compounds continues to advance our understanding in chemical and pharmaceutical sciences.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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N-Nitroso-N-methyl-N-tetradecylamine | 75881-20-8 | C15H32N2O |
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2,4,6-Undecatrienal,2-nitrosohydrazone, (2E,4E,6E)- | 76896-81-6 | C11H17N3O |
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2H-1,2-Oxazine,3,6-dihydro-2-nitroso- | 3276-41-3 | C4H6N2O2 |
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N-Butyl-N-(4-hydroxybutyl)nitrosamine | 3817-11-6 | C8H18N2O2 |
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N-Nitrosodiethylamine | 55-18-5 | C4H10N2O |
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N-Nitrosobis(2-oxopropyl)amine | 60599-38-4 | C6H10N2O3 |
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1-Butanamine,N-nitroso-N-propyl- | 25413-64-3 | C7H16N2O |
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1-Hexanamine,N-methyl-N-nitroso- | 28538-70-7 | C7H16N2O |
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N-Nitroso-methyl-isobutyl-amine | 34419-76-6 | C5H12N2O |
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N-Methyl-N-nitroso-ethenamine | 4549-40-0 | C3H6N2O |
Related Literature
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Brindha J.,Balamurali M. M.,Kaushik Chanda RSC Adv., 2019,9, 34720-34734
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Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
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Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
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J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
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