Morphinans
Morphinan compounds are a class of natural and synthetic organic compounds derived from the morphine alkaloid structure, featuring a six-membered ring fused to a five-membered heterocycle. The most well-known member of this family is morphine itself, commonly used as an analgesic. Morphinans exhibit a diverse range of pharmacological properties due to their complex chemical structures, which allow for various interactions with receptors in the human body. They are widely studied for their potential therapeutic applications in pain management and other medical fields. Common derivatives include hydromorphone, hydrocodone, and levorphanol, all of which are potent analgesics. Research into morphinan compounds continues to explore new drug designs aimed at enhancing efficacy while minimizing side effects.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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Morphinan-3,6-diol,4,5-epoxy-17-methyl-, (5a,6b)- (9CI) | 26626-12-0 | C17H21NO3 |
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Morphinan-6-one,7,8-didehydro-4-hydroxy-3-methoxy-17-methyl- | 467-98-1 | C18H21NO3 |
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14a-Morphinan-6a-ol, 7,8-didehydro-4,5a-epoxy-3-methoxy-17-methyl-,hydrobromide (8CI) | 16206-71-6 | C18H22BrNO3 |
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Morphinan-3-ol,6-(acetylthio)-7,8-didehydro-4,5-epoxy-17-methyl-, (5a,6b)- (9CI) | 117152-64-4 | C19H21NO3S |
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Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl-, (5a,6b)- (9CI) | 143-70-4 | C17H19NO3 |
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l-DROMORAN TARTRATE | 125-72-4 | C21H29NO7 |
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Morphinan-3,6-diol,4,5-epoxy-, (5a,6a)- | 1421-13-2 | C16H19NO3 |
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Dextrorphan Tartrate Salt | 143-98-6 | C21H29NO7 |
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(5alpha)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one | 84116-46-1 | C16H15NO4 |
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N-methylnalorphine | 4121-75-9 | C20H24NO3 |
Related Literature
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Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
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Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
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Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
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