Lupinine-type alkaloids are a class of bioactive compounds found primarily in leguminous plants, such as alfalfa and soybeans. These alkaloids exhibit a range of pharmacological activities including anti-inflammatory, antioxidant, and antimicrobial properties. Structurally, lupinine features a tricyclic skeleton with an isoquinoline core and substitutions at various positions, contributing to its diverse biological effects. Research has shown that these compounds may have potential therapeutic applications in managing inflammatory diseases and infections. Additionally, due to their structural complexity, they are of significant interest in synthetic chemistry for the development of new drugs.