Indolines
Indolines are a class of heterocyclic compounds characterized by the presence of an indole ring, which consists of a benzene ring fused to a pyrrole ring. These molecules are known for their diverse chemical and biological properties, making them of significant interest in both academic research and pharmaceutical applications.
Structurally, indolines can vary based on the substitution pattern on the indole ring. Common substituents include methyl groups, hydroxyl, amino, and carboxylic acid functionalities. Due to their structural flexibility, indolines exhibit a wide range of biological activities, including potential use as antiviral agents, anticancer drugs, and neuroprotective compounds.
Indolines are often synthesized through multistep organic reactions such as condensation, ring closure, and functional group manipulation. Their synthesis methods can be optimized for the desired substituents to tailor their properties for specific applications.
In summary, indolines represent a versatile class of heterocycles with promising potential in various fields, including medicinal chemistry, materials science, and natural product research.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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N,N-Didesethyl Sunitinib | 873077-70-4 | C18H20ClFN4O2 |
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GSK 3B Inhibitor IX | 710323-58-3 | C16H10BrN3O2 |
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2H-Indol-2-one, 6-ethenyl-1,3-dihydro- | 297756-30-0 | C10H9NO |
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(S,Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxy-3-morpholinopropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide | 452105-23-6 | C23H27FN4O4 |
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2,3-dioxo-2,3-dihydro-1H-indole-5-sulfonyl chloride | 132898-96-5 | C8H4ClNO4S |
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SU9516 | 377090-84-1 | C13H11N3O2 |
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6-Chloro-5-methylindoline-2,3-dione | 96187-75-6 | C9H6ClNO2 |
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5-bromo-7-fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-2-one | 872141-26-9 | C10H9BrFNO |
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5,6-dimethyl-2,3-dihydro-1H-indole-2,3-dione | 73816-46-3 | C10H9NO2 |
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3aH-Furo[2,3-b]indol-3a-ol,8a-(5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl)-2,3,8,8a-tetrahydro- (9CI) | 77549-88-3 | C19H24N2O2 |
Related Literature
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Stephen P. Fletcher,Richard B. C. Jagt,Ben L. Feringa Chem. Commun., 2007, 2578-2580
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Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
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Jing Chen,Yu Shao,Danzhen Li J. Mater. Chem. A, 2017,5, 937-941
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Yaqing Liu,Jiangtao Ren,Jing Li,Jiyang Liu,Erkang Wang Chem. Commun., 2012,48, 802-804
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Li-Hua Gan,Rui Wu,Jian-Lei Tian,Patrick W. Fowler Phys. Chem. Chem. Phys., 2017,19, 419-425
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