Hexose phosphates
Hexose phosphates are a class of carbohydrates that contain a hexose sugar (such as glucose, fructose, or ribose) covalently linked to a phosphate group. These molecules play critical roles in various biological processes within living organisms. In metabolic pathways, hexose phosphates serve as pivotal intermediates; for example, they are key components in the glycolytic pathway and pentose phosphate pathway. The phosphorylated form of glucose, known as glucose-6-phosphate (G6P), is particularly important as it acts not only as a storage form of glucose but also as an essential substrate for further metabolic reactions.
Structurally, hexose phosphates exhibit distinct chemical properties due to the presence of the negatively charged phosphate group. This characteristic allows them to participate in numerous enzymatic reactions and serve as second messengers in cellular signaling pathways. Additionally, their role in energy transfer is significant, facilitating the conversion of glucose into usable energy forms within cells.
In industrial applications, hexose phosphates find use in biochemical research, food science, and pharmaceuticals. Their ability to enhance solubility, act as buffers, or serve as substrates for enzymatic reactions makes them valuable tools in laboratory settings and manufacturing processes.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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Mannose-6-phosphate | 723729-16-6 | C6H13O9P |
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6-o-phosphono-d-glucopyranose | 3458-17-1 | C6H13O9P |
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D-Fructose,6-(dihydrogen phosphate) | 643-13-0 | C6H13O9P |
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D-F6P | 73544-42-0 | C6H13O9P |
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2'-Adenylic acid,3'-O-(3,4-di-O-phosphono-a-D-glucopyranosyl)- | 149091-92-9 | C16H26N5O18P3 |
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D-FRUCTOSE 1,6-DIPHOSPHATE-UL-14C TETRASODIUM SALT | 87932-52-3 | C6H14O12P2 |
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(2-Acetamido-2-deoxy-α-D-glucopyranos-1-yl)(methyl 2-acetamido-2-deoxy-α-D-glucopyranosid-6-yl) phosphate | 393167-89-0 | C17H31N2O14P |
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D-glucosamine 6-phosphate | 6815-93-6 | C6H14NO8P |
Related Literature
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Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
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Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
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Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
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Yiding Jiao,Liqun Kang,Jasper Berry-Gair,Kit McColl,Jianwei Li,Haobo Dong,Hao Jiang,Ryan Wang,Furio Corà,Dan J. L. Brett,Ivan P. Parkin J. Mater. Chem. A, 2020,8, 22075-22082
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Brindha J.,Balamurali M. M.,Kaushik Chanda RSC Adv., 2019,9, 34720-34734
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